专利名称：STRUCTURED SUBSTRATES FOR IMPROVING
DETECTION OF LIGHT EMISSIONS ANDMETHODS RELATING TO THE SAME
发明人：M. Shane BOWEN,Dajun YUAN申请号：US15564174申请日：20160414
公开号：US20180119139A1公开日：20180503
专利附图：
摘要：A structured substrate () including a substrate body () having an active side ().The substrate body () includes reaction cavities or sites () that open along the active side
() and interstitial regions () that separate the reaction cavities (). The structured substrate() includes an ensemble amplifier () positioned within each of the reaction cavities (). Theensemble amplifier () includes a plurality of nanostructures (), such as dimers, trimers,bowtie nanoantenna, nanorods, nanorings, nanoplugs, configured to at least one ofamplify electromagnetic energy () that propagates into the corresponding reaction cavity() or amplify electromagnetic energy (), such as emitted fluorescence, that is generatedwithin the corresponding reaction cavity (). Preferably the nanostructures () within thecavities () are covered with a organic material such as a gel (). Preferably nanoimprintlithography (NIL) is used for manufacturing the structured substrate ().
申请人：Illumina, Inc.
地址：San Diego CA US
国籍：US
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